A pde-5 inhibitor (or phosphodiesterase type 5 inhibitor) is a type of drug that is used to inhibit, stop or block the action of PDE5 on cyclic GMP which is present mainly in the smooth muscles that line the blood vessels supplying the penile corpus cavernosum. A pde-5 inhibitor is primarily made for the treatment of male impotence or erectile dysfunction in men, and the very first pde-5 inhibitor (specifically Viagra or sildenafil) was the first effective oral treatment made available in the market for the condition. Due to the fact that PDE5 is actually also existing in the smooth muscles found in the lungs, a pde-5 inhibitor is also being studied for trying to treat pulmonary hypertension, a type of disease wherein the blood vessels located in the lungs become bombarded with fluid, typically as an outcome of the malfunction of the human heart’s right ventricle.
Men who are aware of what a pde-5 inhibitor is have been familiar with different types of pde-5 inhibitors out there. For instance, Viagra (sildenafil) has been the most popular and well-known among all the pde-5 inhibitors, but due to the presence of other pde-5 inhibitors in the market these days, men who would like to try a pde-5 inhibitor would have more options.
Names of Different PDE-5 Inhibitor available in the Market Now
Viagra (sildenafil citrate) – a pde-5 inhibitor available since 1998. The primary purpose of this pde-5 inhibitor is for the treatment of male impotence, erectile dysfunction, or the inability to acquire and maintain erection that is satisfactory enough to complete sexual intercourse. Viagra is used not only as a pde-5 inhibitor, but also in patients with pulmonary arterial hypertension (PAH). This pde-5 inhibitor relaxes the arterial wall in the lungs, thereby decreasing resistance and pressure, thereby lowering the workload of the heart’s right ventricle and it improves the signs and symptoms associated with right-sided heart failure. Also, this pde-5 inhibitor is very useful for mountain climbers as it can help them prevent and treat pulmonary edema related to altitude sickness. Viagra is a type of pde-5 inhibitor that is available in dosages 25, 50 and 100mg, and it is to be taken not more than once a day between 30 minutes and 4 hours just before engaging in sexual activity.
Cialis (tadalafil) – a pde-5 inhibitor approved in October 2011. Aside from being able to treat erectile dysfunction, it can also treat benign prostatic hypertrophy. This pde-5 inhibitor is available in dosages: 2.5, 5, 10, and 20 mg. This pde-5 inhibitor is the only one of all that is offered as a once-daily medication, thereby it is considered as an “as needed” medicine.
Levitra (vardenafil) – a pde-5 inhibitor available around 2005. Aside from being able to treat erectile dysfunction, this pde-5 inhibitor can also be effective in treating premature ejaculation, where it may notably increase the timeframe from vaginal penetration to ejaculation.
Stendra (avanafil) – a PDE5 inhibitor approved in 2013. What makes this pde-5 inhibitor different from the other pde-5 inhibitors is that it has a very fast-acting effect. Because this pde-5 inhibitor is absorbed quickly into the system, most users are able to have successful intercourse within 15 minutes.
In case you are having problems with successful erection, you should consider trying a pde-5 inhibitor. Keep in mind that you should research first all about its benefits and side effects, and if you could afford to visit your doctor, ask him for advice on what to do to help you solve your problem with erectile dysfunction.